TCR-Nck Modulators: Pioneering Oral Modulation of T Cell Receptor Activation Holding the Promise of Treating Autoimmune Diseases

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Christopher VanDeusen presented data on the mechanism of action of AX-158, a first-in-class Nck modulator, at ACR Convergence 2024. The mechanism of AX-158 holds broad potential to treat various autoimmune diseases without causing immunosuppression.