Professor of Immunology at Harvard Medical School and Chief, Immunology at BIDMC.  Dr. Terrhorst’s laboratory is interested in the assembly and signal transduction of the T cell receptor for antigen. They examine the role of the CD3 genes in thymocyte development and in T cell function in mice in which the CD3 genes have been eliminated by homologous recombination techniques. In addition, the mechanisms that govern expression of the three CD3 genes in early T cells are being studied.  Dr. Terrhorst received his PhD degree in molecular biology from the University of Leiden, The Netherlands.